Drugs / cintredekin besudotox

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT00880061 Apr 2009 → Jun 2015 brain neoplasm, glioma National Institute of Neurological Disorders and Stroke (NINDS) Terminated No outcome recorded
Phase 1 NCT00089427 Jul 2004 → Jul 2007 anaplastic astrocytoma, glioblastoma, oligoastrocytoma INSYS Therapeutics Inc Completed No outcome recorded
Phase 1 NCT00064779 Jul 2003 → Jun 2006 anaplastic astrocytoma, anaplastic oligodendroglioma, glioblastoma, oligoastrocytoma INSYS Therapeutics Inc Completed No outcome recorded
Phase 1 NCT00036972 Nov 2001 → Jan 2005 central nervous system neoplasm Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 1 NCT00024557 Jun 2001 → Jun 2006 anaplastic astrocytoma, glioblastoma, oligoastrocytoma INSYS Therapeutics Inc Completed No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT00053040 Oct 2005 → ? central nervous system cancer Pediatric Brain Tumor Consortium Withdrawn No outcome recorded
Phase 1/2 NCT00041587 Jul 2002 → Jun 2006 anaplastic astrocytoma, glioblastoma, oligoastrocytoma INSYS Therapeutics Inc Completed No outcome recorded
Phase 1/2 NCT00024570 Nov 2000 → Jul 2007 anaplastic astrocytoma, glioblastoma, oligoastrocytoma INSYS Therapeutics Inc Completed No outcome recorded
Phase 1/2 NCT00006268 Oct 2000 → Mar 2005 central nervous system neoplasm New Approaches to Brain Tumor Therapy Consortium Completed No outcome recorded
Phase 1/2 NCT00378235 malignant glioma INSYS Therapeutics Inc Withdrawn No outcome recorded
Phase 31 trial
Phase 3 NCT00076986 Feb 2004 → Mar 2007 glioblastoma INSYS Therapeutics Inc Completed No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as cintredekin besudotox ClinicalTrials.gov intervention name — accepted as the source's own label NCT00053040
2

NCT00006268

NCT00036972

Known as Cintredekina besudotox ChEMBL registry synonym — accepted as the source's own label CHEMBL2108583
Known as Cintredekine besudotox ChEMBL registry synonym — accepted as the source's own label CHEMBL2108583
Known as IL-13-PE38 ChEMBL registry synonym — accepted as the source's own label CHEMBL2108583
Known as IL13-PE38QQR ClinicalTrials.gov intervention name — accepted as the source's own label NCT00064779
7

NCT00076986

NCT00880061

NCT00089427

NCT00041587

NCT00024570

NCT00024557

NCT00378235

Action Deplete “Immunotoxins can locate tumor cells and kill them without harming normal cells.” NCT00006268
Action Inhibit “Elongation factor 2 inhibitor” CHEMBL2108583
Modality Protein / enzyme biologic “interleukin-13 PE38QQR immunotoxin” NCT00006268
Route Other “receive interleukin-13 PE38QQR immunotoxin interstitially over 96 hours” NCT00006268
Target EEF2 “Elongation factor 2 inhibitor” CHEMBL2108583
Target IL13RA2 “Interleukin-13 receptor subunit alpha-2 binding agent” CHEMBL2108583