Drugs / STAT3 decoy
last change Jun 2012 re-read 3 minutes ago

STAT3 decoy

Oligonucleotide (other) targets STAT3 via inhibition

Investigated by
University of Pittsburgh

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT00696176 Aug 2008 → Aug 2011 head and neck cancer University of Pittsburgh Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as STAT3 decoy “First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.” PMID 22719020 ↗ Jun 2012
1

NCT00696176 ↗

Action Inhibit “inhibit tumor STAT3 signaling” PMID 22719020 ↗ Jun 2012
Modality Oligonucleotide (other) “STAT3 decoy oligonucleotide” PMID 22719020 ↗ Jun 2012
Route Other “single dose of intratumoral STAT3 decoy” NCT00696176 ↗
Target STAT3 “We developed a decoy targeting STAT3 and conducted a phase 0 trial.” PMID 22719020 ↗ Jun 2012