Drugs / ONCR-177
last change May 2023 re-read 3 minutes ago

ONCR-177

Developed for
colorectal carcinoma · head and neck squamous cell carcinoma · melanoma · skin cancer · triple-negative breast carcinoma
Investigated by
Merck Sharp & Dohme LLC · Oncorus, Inc.

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04348916 May 2020 → May 2023 colorectal carcinoma, head and neck squamous cell carcinoma, melanoma, skin cancer +1 Oncorus, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ONCR-177 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04348916 ↗
Action Inhibit “ONCR-177 is armed with five transgenes for IL12, FLT3LG (extracellular domain), CCL4, and antagonists to immune checkpoints PD-1 and CTLA-4.” PMID 33355229 ↗ Dec 2020
Route Other “Intratumorally administered oncolytic immunotherapy comprised of a genetically engineered HSV-1” NCT04348916 ↗