Drugs / 99mTc-p5+14
last change Dec 2025 re-read 3 minutes ago

99mTc-p5+14

Peptide

Investigated by
Attralus, Inc. · University of Tennessee Graduate School of Medicine

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05951816 Jul 2023 → Dec 2024 amyloidosis University of Tennessee Graduate School of Medicine Unknown No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2025-09-08 Attralus, Inc. Results Attralus Presents New Data on Its Pan-Amyloid Diagnostic Imaging Candidates at ASNC 2025 attralus.com ↗
AT-05 (99mTc-p5+14), a pan-amyloid radiotracer, designed for SPECT imaging, demonstrated high levels of sensitivity and specificity for detection of cardiac amyloid in AL and ATTR patients
2025-04-01 Attralus, Inc. Results Attralus Presents New Data on Its Pan-Amyloid Diagnostic Candidates at the 2025 American College of Cardiology (ACC) Annual Scientific Session attralus.com ↗
AT-05 (99mTc-p5+14), a radiotracer, designed for SPECT imaging, demonstrated high levels of sensitivity and specificity for detection of cardiac amyloid in AL and ATTR patients.
2022-09-08 Attralus, Inc. Results Attralus Announces Presentation of Clinical Data for AT-01 (Iodine (I-124) Evuzamitide), a Novel Amyloid-Specific Imaging Agent, at the 18th International Symposium on Amyloidosis attralus.com ↗
99mTc-p5+14 detected hepatosplenic AA amyloid, the major sites of amyloid deposition in a murine model of the disease, as well as the scant deposits in the hearts of AA mice using ex vivo SPECT/CT imaging of isolated heart.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as 99mTc-p5+14 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05951816 ↗
Modality Peptide “99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m.” NCT05951816 ↗
Route Intravenous “single IV dose of up to 1 mg of 99mTc-p5+14” NCT05951816 ↗