Drugs / NCX 470
last change Jun 2025 re-read 2 minutes ago

NCX 470

also known as bimatoprost
Developed for
ocular hypertension · open-angle glaucoma
Investigated by
Nicox Ophthalmics, Inc.

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT03657797 Aug 2018 → Aug 2019 ocular hypertension, open-angle glaucoma Nicox Ophthalmics, Inc. Completed No outcome recorded
Phase 32 trials
Phase 3 NCT04630808 Nov 2020 → Apr 2025 ocular hypertension, open-angle glaucoma Nicox Ophthalmics, Inc. Completed No outcome recorded
Phase 3 NCT04445519 Jun 2020 → Sep 2022 ocular hypertension, open-angle glaucoma Nicox Ophthalmics, Inc. Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2/3 NCT05938699 Comparator Dec 2023 → Mar 2025 open-angle glaucoma Nicox Ophthalmics, Inc. Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as NCX 470 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03657797
3

NCT04445519

NCT05938699

NCT04630808

Known as bimatoprost “A phase 3 adaptive dose selection trial of NCX 470, a nitric oxide-donating bimatoprost for open-angle glaucoma or ocular hypertension: The MONT BLANC study.” PMID 39477206 Oct 2024
Route Topical “dosed topically to both eyes once daily” PMID 39477206 Oct 2024