Drugs / SY-5609
last change Mar 2023 re-read 9 days ago

SY-5609

Small molecule targets CDK7 via inhibition

Developed for
breast cancer · colorectal cancer · malignant pancreatic neoplasm · small cell lung carcinoma
Investigated by
Hoffmann-La Roche · Syros Pharmaceuticals

Trials 2

20202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04929223 Oct 2021 → Aug 2030 expected colorectal cancer Hoffmann-La Roche Recruiting No outcome recorded
Phase 1 NCT04247126 Jan 2020 → Jan 2023 breast cancer, malignant pancreatic neoplasm, small cell lung carcinoma Syros Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as SY 5609 “A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors” NCT04247126 ↗
2

NCT04929223 ↗

NCT04247126 ↗

Action Inhibit “potent inhibition of CDK7 in cells” PMID 34726887 ↗ Nov 2021
Modality Small molecule — CHEMBL5090754 ↗
Route Oral “An oral CDK7 Inhibitor” NCT04247126 ↗
Target CDK7 “inhibitor of CDK7” PMID 34726887 ↗ Nov 2021