Drugs / SY-5609
last change Mar 2023 re-read 2 minutes ago

SY-5609

Small molecule targets CDK7 via inhibition

Developed for
breast cancer · colorectal cancer · malignant pancreatic neoplasm · small cell lung carcinoma
Investigated by
Hoffmann-La Roche · Syros Pharmaceuticals

Trials 2 · a red edge is where a trial was stopped

20202021202220232024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04929223 Oct 2021 → Aug 2030 expected colorectal cancer Hoffmann-La Roche Recruiting No outcome recorded
Phase 1 NCT04247126 Jan 2020 → Jan 2023 breast cancer, malignant pancreatic neoplasm, small cell lung carcinoma Syros Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as SY 5609 “A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors” NCT04247126
2

NCT04247126

NCT04929223

Action Inhibit “potent inhibition of CDK7 in cells” PMID 34726887 Nov 2021
Modality Small molecule CHEMBL5090754
Route Oral “An oral CDK7 Inhibitor” NCT04247126
Target CDK7 “inhibitor of CDK7PMID 34726887 Nov 2021