Drugs / ORIC-101
last change Dec 2023 re-read 9 days ago

ORIC-101

Small molecule targets GPC3

Developed for
cancer · hepatocellular carcinoma · prostate neoplasm
Investigated by
ORIC Pharmaceuticals · OriCell Therapeutics Co., Ltd.

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials · 1 missed
Phase 1 NCT04033328 Oct 2019 → Nov 2022 prostate neoplasm ORIC Pharmaceuticals Terminated Missed primary
Phase 1 NCT03928314 May 2019 → Sep 2022 cancer ORIC Pharmaceuticals Terminated No outcome recorded
Phase 1 NCT03835637 Mar → Jul 2018 — ORIC Pharmaceuticals Completed No outcome recorded
Phase 1 NCT03324555 Oct → Dec 2017 — ORIC Pharmaceuticals Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05652920 Dec 2022 → Dec 2026 expected hepatocellular carcinoma OriCell Therapeutics Co., Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ORIC-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03928314 ↗
4

NCT03835637 ↗

NCT04033328 ↗

NCT05652920 ↗

NCT03324555 ↗

Action Inhibit “oral GR antagonist ORIC-101” NCT03835637 ↗
Modality Small molecule “ORIC-101 is a small molecule GR antagonist” NCT03928314 ↗
Route Oral “ORIC-101 oral suspension” NCT03324555 ↗
Target GPC3 “GPC3-directed chimeric antigen receptor modified T cells” NCT05652920 ↗