Drugs / Minzasolmin
last change Mar 2025 re-read 2 minutes ago

Minzasolmin

also known as UCB0599 · DLX-313 · Minzasolmina · Minzasolmine

Small molecule

Developed for
Parkinson disease
Investigated by
UCB Biopharma SRL · The Parkinson Study Group · UCB Biopharma S.P.R.L.

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT06533475 Sep → Nov 2024 UCB Biopharma SRL Completed No outcome recorded
Phase 1 NCT05845645 May 2023 → Apr 2024 UCB Biopharma SRL Completed No outcome recorded
Phase 1 NCT04875962 May 2019 → Feb 2020 Parkinson disease UCB Biopharma S.P.R.L. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05543252 Aug 2022 → Mar 2025 Parkinson disease UCB Biopharma SRL Terminated No outcome recorded
Phase 2 NCT04658186 Dec 2020 → Sep 2024 Parkinson disease UCB Biopharma SRL Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Minzasolmin Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant small molecule ASYN misfolding inhibitor in clinical development as a disease-modifying therapeutic for...” PMID 37460603 Jul 2023
3

“Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599).” PMID 38110790 Dec 2023

NCT06533475

NCT05543252

Known as DLX-313 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095072
Known as Minzasolmina ChEMBL registry synonym — accepted as the source's own label CHEMBL5095072
Known as Minzasolmine ChEMBL registry synonym — accepted as the source's own label CHEMBL5095072
Known as UCB0599 “Minzasolmin (UCB0599)” NCT05543252
3

NCT04875962

NCT04658186

NCT05845645

Action Inhibit “small molecule ASYN misfolding inhibitor” PMID 37460603 Jul 2023
Modality Small molecule “an orally bioavailable and brain-penetrant small molecule ASYN misfolding inhibitor” PMID 37460603 Jul 2023
Route Oral “Route of administration: Oral use” NCT04658186