drugset
Drugs / Liprotamase
last change Jun 2018 re-read 3 minutes ago

Liprotamase

also known as ALTU-135 · Theraclec · Trizytek

Protein / enzyme biologic

Developed for
exocrine pancreatic insufficiency · cystic fibrosis
Investigated by
Anthera Pharmaceuticals · Cystic Fibrosis Foundation

Trials 8

today NCT03051490 · Ph 3 NCT02823964 · Ph 4 NCT02734810 · Ph 3 NCT02279498 · Ph 3 NCT00500084 · Ph 3 NCT00449904 · Ph 3 NCT00449878 · Ph 3 NCT00095732 · Ph 2
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00095732 Jun 2004 → Mar 2005 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded
Phase 36 trials
Phase 3 NCT03051490 Apr 2017 → Feb 2018 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Unknown No outcome recorded
Phase 3 NCT02734810 Jun → Dec 2016 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded
Phase 3 NCT02279498 Jun 2015 → Oct 2016 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded
Phase 3 NCT00500084 Dec 2007 → Mar 2009 exocrine pancreatic insufficiency Anthera Pharmaceuticals Terminated No outcome recorded Stop: Business
Phase 3 NCT00449904 Jun 2007 → Apr 2009 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded
Phase 3 NCT00449878 May 2007 → Jun 2008 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded
Phase 41 trial
Phase 4 NCT02823964 Sep 2016 → Mar 2018 cystic fibrosis, exocrine pancreatic insufficiency Anthera Pharmaceuticals Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as Liprotamase ClinicalTrials.gov intervention name — accepted as the source's own label NCT00449878 ↗
7

NCT00500084 ↗

NCT02279498 ↗

NCT00449904 ↗

NCT02823964 ↗

NCT02734810 ↗

NCT00095732 ↗

NCT03051490 ↗
Known as ALTU-135 ChEMBL registry synonym — accepted as the source's own label CHEMBL2108703 ↗
Known as Theraclec ChEMBL registry synonym — accepted as the source's own label CHEMBL2108703 ↗
Known as Trizytek ChEMBL registry synonym — accepted as the source's own label CHEMBL2108703 ↗
Action Restore “pancreatic enzyme replacement” NCT02823964 ↗
Modality Protein / enzyme biologic “new enzyme therapy” NCT00095732 ↗
Route Oral “Administered orally as either Size 2 capsules (20,000 Units lipase; 20,000 Units protease; and 3,000 Units amylase) or Size 5 capsules (5,000 Units lipase; 5,000 Units...” NCT00095732 ↗