Drugs / XL844
last change Dec 2008 re-read 3 minutes ago

XL844

targets CHEK1, CHEK2 via inhibition

Developed for
cancer · chronic lymphocytic leukemia/small lymphocytic lymphoma · lymphoma
Investigated by
Exelixis

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00475917 May 2007 → Dec 2008 cancer, lymphoma Exelixis Terminated No outcome recorded
Phase 1 NCT00234481 — chronic lymphocytic leukemia/small lymphocytic lymphoma Exelixis Terminated No outcome recorded Stop: Enrollment

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as XL844 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00234481 ↗
1

NCT00475917 ↗

Action Inhibit “Serine/threonine-protein kinase Chk2 inhibitor” CHEMBL3544936 ↗
1

“Serine/threonine-protein kinase Chk1 inhibitor” CHEMBL3544936 ↗

Route Oral “XL844 Administered Orally to Subjects With Chronic Lymphocytic Leukemia” NCT00234481 ↗
Target CHEK1 “Serine/threonine-protein kinase Chk1 inhibitor” CHEMBL3544936 ↗
Target CHEK2 “Serine/threonine-protein kinase Chk2 inhibitor” CHEMBL3544936 ↗