Drugs / Nemonoxacin
Nemonoxacin
also known as
TG-873870 · Nemonoxacin Malate Sodium Chloride · NEMONOXACIN MALIC ACID · Nemonoxacine · Nemonoxacino
Trials 10 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 13 trials | ||||||
| Phase 1 | NCT02840812 | Apr 2017 → Jan 2019 | impaired renal function disease | Zhejiang Medicine Co., Ltd. | Unknown | No outcome recorded |
| Phase 1 | NCT02604498 | Apr 2016 → Jan 2018 | liver disorder | Zhejiang Medicine Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT03362853 | Jun → Aug 2012 | — | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT01944774 | Mar → Dec 2013 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT00685698 | Jun 2008 → Apr 2009 | — | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT00434291 | Dec 2006 → Aug 2007 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT03551210 | May 2016 → Dec 2017 | bacterial pneumonia | R-Pharm | Completed | No outcome recorded |
| Phase 3 | NCT02205112 | Jun 2014 → May 2017 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT01529476 | Apr 2011 → Aug 2012 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05133752 | Sep 2018 → Mar 2020 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT01529957 Comparator | Sep 2008 → Mar 2011 | — | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT01395108 Comparator | Jan → Aug 2008 | — | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT01537250 Comparator | Aug 2009 → Aug 2010 | pneumonia | TaiGen Biotechnology Co., Ltd. | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 16 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Nemonoxacin | “TG-873870 (Nemonoxacin)” NCT00685698 ↗ |
| Known as | Nemonoxacin Malate Sodium Chloride | “Nemonoxacin Malate Sodium Chloride,intravenous injection,once daily” NCT01529957 ↗ |
| Known as | NEMONOXACIN MALIC ACID | ChEMBL registry synonym — accepted as the source's own label CHEMBL1213456 ↗ |
| Known as | Nemonoxacine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1213456 ↗ |
| Known as | Nemonoxacino | ChEMBL registry synonym — accepted as the source's own label CHEMBL1213456 ↗ |
| Known as | TG-873870 | “Nemonoxacin (TG-873870) is a novel nonfluorinated quinolone with potent broad-spectrum activity against Gram-positive, Gram-negative, and atypical pathogens, including...” PMID 25092690 ↗ Aug 20144“TG-873870 (Nemonoxacin), a non-fluorinated quinolone (NFQ), is a selective bacterial topoisomerase inhibitor.” NCT01529476 ↗ “TG-873870 (Nemonoxacin), a non-fluorinated quinolone (NFQ), is a selective bacterial topoisomerase inhibitor.” NCT02205112 ↗ “TG-873870(Nemonoxacin)” NCT00434291 ↗ |
| Action | Inhibit | “is a selective bacterial topoisomerase inhibitor” NCT00434291 ↗ |
| Modality | Small molecule | “TG-873870(Nemonoxacin), a non-fluorinated quinolone (NFQ)” NCT00434291 ↗ |
| Route | Oral | “following single and multiple oral doses” PMID 22650326 ↗ Jul 2012 |