Drugs / Karonudib
last change Dec 2024 re-read 3 minutes ago

Karonudib

also known as TH1579
Developed for
cancer · leukemia
Investigated by
Thomas Helleday Foundation

Trials 2

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04077307 Dec 2019 → Dec 2026 expected leukemia Thomas Helleday Foundation Recruiting No outcome recorded
Phase 1 NCT03036228 Jan 2017 → Dec 2024 cancer Thomas Helleday Foundation Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Karonudib ClinicalTrials.gov intervention name — accepted as the source's own label NCT04077307 ↗
1

NCT03036228 ↗

Known as TH1579 “To determine the safety and tolerability of Karonudib (TH1579) in escalating doses for the treatment of patients with advanced solid malignant tumours.” NCT03036228 ↗
Action Inhibit “Karonudib is an oral inhibitor of MTH1 supplied as an oral solution and now as tablets.” NCT03036228 ↗
Route Oral “Karonudib is an oral inhibitor of MTH1 supplied as an oral solution and now as tablets.” NCT03036228 ↗