Drugs / Recombinant Human Prolactin
Recombinant Human Prolactin
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT00181649 | Sep 2006 → May 2011 | lactation disease | Massachusetts General Hospital | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT00181623 | Jan 2005 → May 2011 | lactation disease | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT00438490 | Apr 2002 → Mar 2011 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2 | NCT00181610 Comparator | Sep 2004 → Sep 2010 | lactation disease | Massachusetts General Hospital | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Recombinant Human Prolactin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00181623 ↗ |
| Known as | r-hPRL | “The objective of this study was to determine the impact of recombinant human prolactin (r-hPRL) on the nutritional and immunologic composition of breast milk.” PMID 21262884 ↗ Jan 20112“We examined the biological activity and safety of recombinant human prolactin (r-hPRL) as preliminary data for its use to augment lactation.” NCT00438490 ↗ “The efficacy of recombinant human prolactin (r-hPRL) for treatment of primary lactation insufficiency in women with prolactin deficiency” NCT00181623 ↗ |
| Known as | recombinant human PRL | “Recombinant human PRL (r-hPRL) was administered to the patient.” PMID 23940128 ↗ Aug 2013 |
| Action | Restore | “Lactation insufficiency has many aetiologies including complete or relative prolactin deficiency. Exogenous prolactin may increase breast milk volume in this subset.” PMID 20718766 ↗ Nov 2010 |
| Modality | Protein / enzyme biologic | “recombinant human prolactin (r-hPRL)” PMID 21262884 ↗ Jan 2011 |
| Route | Subcutaneous | “prolactin 60 mg/kg or placebo will be injected subcutaneously by the study nurse” NCT00181610 ↗ |