Drugs / AAB-003
last change Mar 2016 re-read 3 minutes ago

AAB-003

also known as PF-05236812

Monoclonal antibody

Developed for
Alzheimer disease
Investigated by
JANSSEN Alzheimer Immunotherapy Research & Development, LLC · Pfizer

Trials 2

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01369225 Jul 2011 → Aug 2014 Alzheimer disease Pfizer Completed No outcome recorded
Phase 1 NCT01193608 Sep 2010 → Oct 2013 Alzheimer disease Pfizer Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as AAB-003 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01193608 ↗
1

NCT01369225 ↗

Known as PF-05236812 “This is a study to evaluate the safety and tolerability of multiple doses of AAB-003 (PF-05236812) in patients with mild to moderate Alzheimer's Disease.” NCT01369225 ↗
1

“This is a study to evaluate the safety of multiple doses of AAB-003 (PF-05236812) in patients with mild to moderate Alzheimer's Disease.” NCT01193608 ↗

Modality Monoclonal antibody “a humanized monoclonal antibody to amyloid β” PMID 26925577 ↗ Mar 2016
Route Intravenous “after intravenous infusions of escalating doses” PMID 26925577 ↗ Mar 2016