Drugs / Pentoxiphylline
last change Mar 2021 re-read 3 minutes ago

Pentoxiphylline

also known as PTX

targets TNF via inhibition

Developed for
alcoholic hepatitis · metabolic dysfunction-associated steatohepatitis
Investigated by
Institute of Liver and Biliary Sciences, India

Trials 2

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 31 trial
Phase 3 NCT01384578 Jul 2011 → Nov 2013 metabolic dysfunction-associated steatohepatitis Institute of Liver and Biliary Sciences, India Withdrawn No outcome recorded Stop: Business
Phase not applicable1 trial
— NCT02458079 Dec 2014 → Jul 2016 alcoholic hepatitis Institute of Liver and Biliary Sciences, India Completed No outcome recorded
Comparator or background therapy1 trial
— NCT02231333 Comparator Jul 2013 → Jul 2015 metabolic dysfunction-associated steatohepatitis Institute of Liver and Biliary Sciences, India Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as pentoxiphylline ClinicalTrials.gov intervention name — accepted as the source's own label NCT02231333 ↗
2

NCT01384578 ↗

NCT02458079 ↗

Known as PTX “Pentoxiphylline (PTX), an anti-TNF-alpha agent, has been reported to reduce hepatic inflammation and fibrosis.” PMID 33772456 ↗ Mar 2021
1

“pentoxiphylline (PTX)” NCT02231333 ↗

Action Inhibit “Pentoxiphylline (PTX), an anti-TNF-alpha agent, has been reported to reduce hepatic inflammation and fibrosis.” PMID 33772456 ↗ Mar 2021
Target TNF “Pentoxiphylline (PTX), an anti-TNF-alpha agent” PMID 33772456 ↗ Mar 2021