Drugs / Masupirdine
last change Nov 2022 re-read 2 minutes ago

Masupirdine

also known as SUVN-502 · Masupirdina

Small molecule targets HTR6 via inhibition

Developed for
Alzheimer disease
Investigated by
Suven Life Sciences Limited

Trials 1 · a red edge is where a trial was stopped

20232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT05397639 Nov 2022 → Dec 2026 expected Alzheimer disease Suven Life Sciences Limited Recruiting No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02580305 Comparator Sep 2015 → Nov 2019 Alzheimer disease Suven Life Sciences Limited Completed No outcome recorded
Phase not stated1 trial
NCT03564964 Background Alzheimer disease Suven Life Sciences Limited No longer available No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Masupirdine ClinicalTrials.gov intervention name — accepted as the source's own label NCT05397639
Known as Masupirdina ChEMBL registry synonym — accepted as the source's own label CHEMBL4117187
Known as SUVN-502 “A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel Group, Multicenter Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Masupirdine...” NCT05397639
2

NCT02580305

NCT03564964

Action Inhibit “Serotonin 6 (5-HT6) receptor antagonist” CHEMBL4117187
Modality Small molecule CHEMBL4117187
Route Oral “Once-daily, tablets, orally” NCT02580305
Target HTR6 “Serotonin 6 (5-HT6) receptor antagonist” CHEMBL4117187