Drugs / EFMITERMANT ALFA
last change Mar 2020 re-read 3 minutes ago

EFMITERMANT ALFA

also known as ACE-083

Protein / enzyme biologic

Developed for
Charcot-Marie-Tooth disease · facioscapulohumeral muscular dystrophy
Investigated by
Acceleron Pharma, Inc.

Trials 4

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02257489 Sep 2014 → Mar 2016 musculoskeletal system disorder Acceleron Pharma, Inc. Completed No outcome recorded
Phase 23 trials · 2 met primary
Phase 2 NCT03943290 May 2019 → Mar 2020 Charcot-Marie-Tooth disease, facioscapulohumeral muscular dystrophy Acceleron Pharma, Inc. Terminated No outcome recorded
Phase 2 NCT03124459 Jul 2017 → Mar 2020 Charcot-Marie-Tooth disease Acceleron Pharma, Inc. Terminated Met primary
Phase 2 NCT02927080 Nov 2016 → Sep 2019 facioscapulohumeral muscular dystrophy Acceleron Pharma, Inc. Terminated Met primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as EFMITERMANT ALFA ChEMBL registry synonym — accepted as the source's own label CHEMBL4297867 ↗
Known as ACE-083 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03124459 ↗
3

NCT02257489 ↗

NCT03943290 ↗

NCT02927080 ↗

Modality Protein / enzyme biologic “recombinant fusion protein” NCT02257489 ↗
Route Intramuscular “administered unilaterally or bilaterally to either the tibialis anterior (TA) or biceps brachii (BB) muscle(s)” NCT02927080 ↗