Drugs / Progerinin
last change Jul 2026 re-read 2 minutes ago

Progerinin

also known as Progerinina · Progerinine · SLC-D011

Small molecule

Developed for
Hutchinson-Gilford progeria syndrome · Werner syndrome
Investigated by
PRG Science & Technology Co., Ltd. · Amarex Clinical Research

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04512963 Aug 2020 → Jul 2021 Hutchinson-Gilford progeria syndrome, Werner syndrome PRG Science & Technology Co., Ltd. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05847179 Jul 2026 → Dec 2027 expected Werner syndrome PRG Science & Technology Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT06775041 Jan 2025 → Mar 2026 overdue Hutchinson-Gilford progeria syndrome PRG Science & Technology Co., Ltd. Active not recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Progerinin ClinicalTrials.gov intervention name — accepted as the source's own label NCT06775041
2

NCT05847179

NCT04512963

Known as Progerinina ChEMBL registry synonym — accepted as the source's own label CHEMBL1631723
Known as Progerinine ChEMBL registry synonym — accepted as the source's own label CHEMBL1631723
Known as SLC-D011 ChEMBL registry synonym — accepted as the source's own label CHEMBL1631723
Action Inhibit “Progerinin binds specifically to progerin reduces its expression” NCT04512963
Modality Small molecule CHEMBL1631723
Route Oral “100 mg/g nano-suspension for oral use” NCT04512963