Drugs / HYALURONIDASE (OVINE)
HYALURONIDASE (OVINE)
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | VITRASE | — | 2004-05-05 | fda.gov ↗ |
Trials 7
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT00198458 | Jul 2004 | hypersensitivity reaction disease | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 1 | NCT00198419 | Mar 2004 | hypersensitivity reaction disease | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT00198471 | Jul 2005 → Nov 2006 | diabetic retinopathy, vitreous detachment | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT00198484 | Oct → Dec 2004 | — | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 3 | NCT00198497 | Jun 1999 → Sep 2001 | diabetic retinopathy | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 3 | NCT00198510 | Nov 1998 → Sep 2001 | diabetic retinopathy | Bausch & Lomb Incorporated | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00198549 | Sep 2004 → Jan 2005 | — | Bausch & Lomb Incorporated | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | HYALURONIDASE (OVINE) | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Known as | Diffusin | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Known as | Enzodase | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Known as | Hyazyme | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Known as | HYO-6A | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Known as | ovine hyaluronidase | “highly purified, preservative-free, ovine hyaluronidase (Vitrase)” PMID 18441312 ↗ Apr 20081“Vitrase (ovine hyaluronidase) Lyophilized” NCT00198549 ↗ |
| Known as | Vitrase | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00198510 ↗ |
| Known as | Wydase | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108607 ↗ |
| Modality | Protein / enzyme biologic | “highly purified, preservative-free, ovine hyaluronidase (Vitrase)” PMID 18441312 ↗ Apr 2008 |
| Route | Intravitreal | “A single intravitreous injection of Vitrase 93 USP Units (75 IU) on Study Day 1.” NCT00198471 ↗ |