Drugs / re-directed FAP-specific T cells
last change Jul 2019 re-read 3 minutes ago

re-directed FAP-specific T cells

Cell therapy targets FAP

Developed for
malignant pleural mesothelioma
Investigated by
University of Zurich

Trials 1

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT01722149 Feb 2015 → Mar 2019 malignant pleural mesothelioma University of Zurich Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as re-directed FAP-specific T cells “Patients will be treated with 1x10e6 re-directed FAP-specific T cells injected in the pleural effusion.” NCT01722149 ↗
Modality Cell therapy “CD8 positive T cells will be isolated and re-programmed by retroviral transfer of a chimeric antigen receptor (CAR)” NCT01722149 ↗
Route Other “injected in the pleural effusion” NCT01722149 ↗
Target FAP “CAR recognizing FAP which serves as target structure in MPM.” NCT01722149 ↗