Drugs / glasmacinal
last change May 2026 re-read 2 minutes ago

glasmacinal

also known as EP395 · EP395 FREE BASE

Small molecule

Developed for
chronic obstructive pulmonary disease
Investigated by
EpiEndo Pharmaceuticals · FGK Clinical Research GmbH · CTC Clinical Trial Consultants AB

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT06677918 Feb → Aug 2025 EpiEndo Pharmaceuticals Completed No outcome recorded
Phase 1 NCT06118684 Oct 2023 → Jan 2024 chronic obstructive pulmonary disease EpiEndo Pharmaceuticals Completed No outcome recorded
Phase 1 NCT05516316 Oct 2022 → Jun 2023 chronic obstructive pulmonary disease EpiEndo Pharmaceuticals Completed No outcome recorded
Phase 1 NCT04819854 Apr 2021 → Mar 2022 adult acute lymphoblastic leukemia EpiEndo Pharmaceuticals Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05572333 Nov 2022 → Nov 2023 chronic obstructive pulmonary disease EpiEndo Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as glasmacinal “EP395 (glasmacinal), a novel macrolide, is being developed as a treatment to reduce exacerbations of COPD without inducing antimicrobial resistance.” PMID 42206016 May 2026
2

glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions.” PMID 41845869 Mar 2026

glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions.” PMID 41845869 Mar 2026

Known as EP395 “glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions.” PMID 41845869 Mar 2026
4

NCT04819854

NCT05572333

NCT06677918

NCT05516316

Known as EP395 FREE BASE ChEMBL registry synonym — accepted as the source's own label CHEMBL6068055
Modality Small molecule “oral anti-inflammatory macrolide” PMID 41845869 Mar 2026
1

CHEMBL6068055

Route Oral “administered by oral capsules” NCT04819854