Drugs / TUROFEXORATE ISOPROPYL
TUROFEXORATE ISOPROPYL
also known as
FXR 450 · Turofexorate d'isopropyle · Turofexorato de isopropilo · WAY-362450 · XL-335
Small molecule targets NR1H4 via activation
Trials 0
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Comparator or background therapy2 trials | ||||||
| Phase 1 | NCT00509756 Comparator | Nov 2007 → Feb 2008 | — | Wyeth is now a wholly owned subsidiary of Pfizer | Terminated | No outcome recorded |
| Phase 1 | NCT00499629 Comparator | Oct 2007 → Feb 2008 | — | Wyeth is now a wholly owned subsidiary of Pfizer | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | TUROFEXORATE ISOPROPYL | ChEMBL registry synonym — accepted as the source's own label CHEMBL454138 ↗ |
| Known as | FXR 450 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00499629 ↗ |
| Known as | Turofexorate d'isopropyle | ChEMBL registry synonym — accepted as the source's own label CHEMBL454138 ↗ |
| Known as | Turofexorato de isopropilo | ChEMBL registry synonym — accepted as the source's own label CHEMBL454138 ↗ |
| Known as | WAY-362450 | ChEMBL registry synonym — accepted as the source's own label CHEMBL454138 ↗ |
| Known as | XL-335 | ChEMBL registry synonym — accepted as the source's own label CHEMBL454138 ↗ |
| Action | Activate | “Bile acid receptor FXR agonist” CHEMBL454138 ↗ |
| Modality | Small molecule | — CHEMBL454138 ↗ |
| Route | Oral | “FXR-450 Administered Orally to Healthy Subjects” NCT00499629 ↗ |
| Target | NR1H4 | “Bile acid receptor FXR agonist” CHEMBL454138 ↗ |