Drugs / MK-1029
last change Sep 2017 re-read 9 days ago

MK-1029

targets PTGDR2 via inhibition

Developed for
asthma
Investigated by
Merck Sharp & Dohme LLC

Trials 5

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials · 1 met primary
Phase 1 NCT01370317 Jun → Dec 2011 asthma Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 1 NCT01343407 Apr 2011 → Jan 2012 asthma Merck Sharp & Dohme LLC Completed Met primary
Phase 23 trials · 1 met primary · 2 missed
Phase 2 NCT02720081 May 2016 → Aug 2017 asthma Merck Sharp & Dohme LLC Completed Met primary
Phase 2 NCT01656395 Aug 2012 → Jun 2014 asthma Merck Sharp & Dohme LLC Terminated Missed primary
Phase 2 NCT01624974 Aug 2012 → May 2014 asthma Merck Sharp & Dohme LLC Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as MK-1029 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02720081 ↗
4

NCT01343407 ↗

NCT01624974 ↗

NCT01656395 ↗

NCT01370317 ↗

Action Inhibit “G protein-coupled receptor 44 antagonist” CHEMBL3545031 ↗
Route Oral “Five (5) X 100 mg capsules, orally, once daily for 28 days” NCT01370317 ↗
Target PTGDR2 “G protein-coupled receptor 44 antagonist” CHEMBL3545031 ↗