Drugs / PG-102
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PG-102

also known as MG12

Monoclonal antibody targets CD40

Developed for
type 2 diabetes mellitus · psoriatic arthritis · obesity disorder
Investigated by
ProGen. Co., Ltd. · PanGenetics UK Limited

Trials 3 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00787137 Dec 2008 → Apr 2010 psoriatic arthritis PanGenetics UK Limited Terminated No outcome recorded
Phase 22 trials
Phase 2 NCT07187856 Jan → Sep 2026 expected type 2 diabetes mellitus ProGen. Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT06712615 Dec 2024 → Oct 2025 overdue type 2 diabetes mellitus ProGen. Co., Ltd. Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06891287 Comparator Dec 2025 → Dec 2026 expected obesity disorder RANI Therapeutics Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as PG-102 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07187856
3

NCT06891287

NCT00787137

NCT06712615

Known as MG12 “* Participants will receive PG-102 by subcutaneous (SC) injection. * Other Names: MG12NCT06712615
Modality Monoclonal antibody “Anti-CD40 Monoclonal AntibodyNCT00787137
Route Intravenous “A single intravenous infusion” NCT00787137
Target CD40 “Anti-CD40 monoclonal antibody” NCT00787137