Drugs / BRIMAPITIDE
last change Mar 2016 re-read 3 minutes ago

BRIMAPITIDE

also known as XG-102 · Brimapitida

Protein / enzyme biologic targets MAPK10 via inhibition

Investigated by
Xigen SA

Trials 3

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01570205 Jul → Nov 2011 — Xigen SA Completed No outcome recorded
Phase 32 trials
Phase 3 NCT02508337 Jul 2015 → Jan 2016 cataract Xigen SA Completed No outcome recorded
Phase 3 NCT02235272 Sep 2014 → Dec 2015 cataract Xigen SA Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as BRIMAPITIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL4297650 ↗
Known as Brimapitida ChEMBL registry synonym — accepted as the source's own label CHEMBL4297650 ↗
Known as XG-102 “The purpose of this study is to evaluate the clinical efficacy and safety of XG-102 (900µg) compared to vehicle in the treatment of subjects with inflammation and pain...” NCT02235272 ↗
2

NCT02508337 ↗

NCT01570205 ↗

Action Inhibit “c-Jun N-terminal kinase 3 inhibitor” CHEMBL4297650 ↗
Modality Protein / enzyme biologic — CHEMBL4297650 ↗
Route Intravenous “single intravenous infusion” NCT01570205 ↗
Target MAPK10 “c-Jun N-terminal kinase 3 inhibitor” CHEMBL4297650 ↗