Drugs / clofibrate
clofibrate
also known as
Atromid · Atromid-s · AY-61123 · Chlorfenisate · Clofibrato · Ethyl p-chlorophenoxyisobutyrate · ICI 28257 · NSC-79389
Small molecule targets PPARA via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ATROMID-S | — | 1967-02-08 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT00000482 | Apr 1965 → Mar 1985 | coronary artery disorder, myocardial infarction, myocardial ischemia | National Heart, Lung, and Blood Institute (NHLBI) | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00000483 | Jun 1981 → Mar 1985 | coronary artery disorder, myocardial infarction, myocardial ischemia | National Heart, Lung, and Blood Institute (NHLBI) | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | clofibrate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00000483 ↗ |
| Known as | Atromid | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | Atromid-s | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | AY-61123 | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | Chlorfenisate | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | Clofibrato | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | Ethyl p-chlorophenoxyisobutyrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | ICI 28257 | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Known as | NSC-79389 | ChEMBL registry synonym — accepted as the source's own label CHEMBL565 ↗ |
| Action | Activate | “Peroxisome proliferator-activated receptor alpha agonist” CHEMBL565 ↗ |
| Modality | Small molecule | — CHEMBL565 ↗ |
| Target | PPARA | “Peroxisome proliferator-activated receptor alpha agonist” CHEMBL565 ↗ |