Drugs / LDLR mRNA exosomes
LDLR mRNA exosomes
also known as
Exosome-based ldlr mRNA nanoplatform · Low Density Lipoprotein Receptor mRNA Exosomes · low-density lipoprotein receptor mRNA (LDLR mRNA) exosomes
targets LDLR
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT05043181 | Dec 2021 → Dec 2026 expected | familial hypercholesterolemia | Tang-Du Hospital | Not yet recruiting | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 1 source stands behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | LDLR mRNA exosomes | “For the intervention of low-density lipoprotein receptor mRNA (LDLR mRNA) exosomes.” NCT05043181 ↗ |
| Known as | Exosome-based ldlr mRNA nanoplatform | “This first-in-human study is aimed to evaluate the safety and preliminary effectiveness of Exosome-based ldlr mRNA nanoplatform for gene therapy in HoFH.” NCT05043181 ↗ |
| Known as | Low Density Lipoprotein Receptor mRNA Exosomes | “Biological: Low Density Lipoprotein Receptor mRNA Exosomes” NCT05043181 ↗ |
| Known as | low-density lipoprotein receptor mRNA (LDLR mRNA) exosomes | “For the intervention of low-density lipoprotein receptor mRNA (LDLR mRNA) exosomes.” NCT05043181 ↗ |
| Route | Intravenous | “the subjects will receive 3 intravenous/peritoneal infusion treatment of LDLR mRNA exosomes once a week for three weeks” NCT05043181 ↗ |
| Target | LDLR | “exosome-based LDLR-gene delivery strategy” NCT05043181 ↗ |