Drugs / LUSVERTIKIMAB
last change Jan 2025 re-read 3 minutes ago

LUSVERTIKIMAB

also known as OSE-127

Monoclonal antibody

Developed for
ulcerative colitis
Investigated by
OSE Immunotherapeutics · Servier

Trials 2

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03980080 Dec 2018 → Nov 2019 — OSE Immunotherapeutics Completed No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT04882007 Oct 2020 → Apr 2024 ulcerative colitis OSE Immunotherapeutics Completed Met primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as LUSVERTIKIMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4650498 ↗
Known as OSE-127 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04882007 ↗
1

NCT03980080 ↗

Action Inhibit “mAb antagonist to CD127 receptor (or IL-7Rα)” NCT03980080 ↗
Modality Monoclonal antibody “mAb antagonist to CD127 receptor (or IL-7Rα)” NCT03980080 ↗
Route Intravenous “Single (IV and SC)” NCT03980080 ↗
Route Subcutaneous “Single (IV and SC)” NCT03980080 ↗