Drugs / MK-8033
last change Jan 2018 re-read 3 minutes ago

MK-8033

also known as CPD 11R

Small molecule targets MET, MST1R via inhibition

Developed for
cancer of unknown primary site
Investigated by
Merck Sharp & Dohme LLC

Trials 1

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00559182 Dec 2007 → Jun 2010 cancer of unknown primary site Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MK-8033 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00559182 ↗
Known as CPD 11R ChEMBL registry synonym — accepted as the source's own label CHEMBL2323775 ↗
Action Inhibit “Macrophage-stimulating protein receptor inhibitor” CHEMBL2323775 ↗
1

“MK-8033 is a small-molecule inhibitor of c-Met” PMID 29376210 ↗ Jan 2018

Modality Small molecule “MK-8033 is a small-molecule inhibitor of c-Met” PMID 29376210 ↗ Jan 2018
Route Oral “MK-8033 will be administered as an oral formulation” NCT00559182 ↗
Target MET “MK-8033 is a small-molecule inhibitor of c-Met” PMID 29376210 ↗ Jan 2018
Target MST1R “Macrophage-stimulating protein receptor inhibitor” CHEMBL2323775 ↗