Drugs / T0001
last change Nov 2017 re-read 9 days ago

T0001

Protein / enzyme biologic targets TNF via inhibition

Developed for
rheumatoid arthritis
Investigated by
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02481180 Jul 2015 → Nov 2017 rheumatoid arthritis Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. Terminated No outcome recorded
Phase 1 NCT02291471 Oct 2014 → Feb 2015 rheumatic disorder Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as T0001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02291471 ↗
1

NCT02481180 ↗

Action Inhibit “T0001 can inhibit the binding of soluble TNFα (sTNFα) or membrane-bound TNFα (mTNFα) to TNF receptors.” PMID 28542350 ↗ May 2017
Modality Protein / enzyme biologic “T0001 is a recombinant human TNFR-Fc fusion protein mutant” PMID 28542350 ↗ May 2017
Route Subcutaneous “injection (SC) T0001 15mg weekly for 12 weeks” NCT02481180 ↗
Target TNF “T0001 can inhibit the binding of soluble TNFα (sTNFα) or membrane-bound TNFα (mTNFα) to TNF receptors.” PMID 28542350 ↗ May 2017