Drugs / TANZISERTIB
last change Aug 2012 re-read 3 minutes ago

TANZISERTIB

also known as CC-930 · JNK 930

Small molecule targets MAPK10, MAPK8, MAPK9 via inhibition

Developed for
discoid lupus erythematosus · idiopathic pulmonary fibrosis · pulmonary fibrosis
Investigated by
Celgene Corporation

Trials 2

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01466725 Nov 2011 → Jul 2012 discoid lupus erythematosus Celgene Corporation Terminated No outcome recorded
Phase 2 NCT01203943 Jan 2011 → Jan 2012 idiopathic pulmonary fibrosis, pulmonary fibrosis Celgene Corporation Terminated No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TANZISERTIB ChEMBL registry synonym — accepted as the source's own label CHEMBL1950289 ↗
Known as CC-930 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01203943 ↗
1

NCT01466725 ↗

Known as JNK 930 ChEMBL registry synonym — accepted as the source's own label CHEMBL1950289 ↗
Action Inhibit “c-Jun N-terminal kinase 1 inhibitor” CHEMBL1950289 ↗
2

“c-Jun N-terminal kinase 3 inhibitor” CHEMBL1950289 ↗

“c-Jun N-terminal kinase 2 inhibitor” CHEMBL1950289 ↗

Modality Small molecule — CHEMBL1950289 ↗
Route Oral “50 mg PO daily up to 56 weeks beginning on Day 1” NCT01203943 ↗
Target MAPK10 “c-Jun N-terminal kinase 3 inhibitor” CHEMBL1950289 ↗
Target MAPK8 “c-Jun N-terminal kinase 1 inhibitor” CHEMBL1950289 ↗
Target MAPK9 “c-Jun N-terminal kinase 2 inhibitor” CHEMBL1950289 ↗