Drugs / PRT811
last change Mar 2023 re-read 3 minutes ago

PRT811

targets PRMT5 via inhibition

Developed for
glioma
Investigated by
Prelude Therapeutics

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04089449 Nov 2019 → Mar 2023 glioma Prelude Therapeutics Completed No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2021-10-07 Prelude Therapeutics Results Prelude Therapeutics Announces Presentation of Encouraging Data from Multiple Programs at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics preludetx.com ↗
We are also encouraged by the preliminary clinical activity observed with both molecules in multiple tumor types, including durable responses in cancers with high unmet need.
2020-11-10 Prelude Therapeutics Results Prelude Therapeutics Announces Third Quarter 2020 Financial Results preludetx.com ↗
Partial Response Confirmed in Glioblastoma Multiforme Patient in Phase 1 Trial of PRT811

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as PRT811 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04089449 ↗
Action Inhibit “PRMT5 inhibitor” NCT04089449 ↗
Route Oral “PRT811 will be administered orally” NCT04089449 ↗
Target PRMT5 “PRMT5 inhibitor” NCT04089449 ↗