Drugs / Thymoquinone
Thymoquinone
also known as
Black Cumin oil · NSC-2228 · P-cymene-2,5-dione · P-mentha-3,6-diene-2,5-dione · Thymoquinon
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT05497895 | Sep → Oct 2022 | gingivitis | King Abdulaziz University | Unknown | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT03208790 | Sep 2017 → Mar 2020 | preneoplastic lesion | Cairo University | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT07313111 | Jul 2024 → Sep 2025 | diabetic polyneuropathy | Hawler Medical University | Completed | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT06508372 | Aug → Dec 2024 overdue | psoriasis | Assiut University | Not yet recruiting | No outcome recorded |
| — | NCT06070311 | Oct 2023 → Sep 2025 | chronic rhinosinusitis, nasal cavity polyp | Assiut University | Unknown | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2/3 | NCT04852510 Comparator | Feb 2019 → Aug 2020 | polycystic ovary syndrome | Saudi German Hospital - Madinah | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Thymoquinone | “thymoquinone will be extracted from Nigella Sativa and packed in buccal tablets of 10mg” NCT03208790 ↗5“participants recieved 65 mg of thymoquinone capsule daily for two months” NCT07313111 ↗ |
| Known as | Black Cumin oil | “Patients in Group B, received a combination of Metformin 500 mg three times daily with meals (Metfor® 500 mg, Metformin hydrochloride tablets. TABUK Pharmaceutical. KSA) and...” NCT04852510 ↗ |
| Known as | NSC-2228 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1672002 ↗ |
| Known as | P-cymene-2,5-dione | ChEMBL registry synonym — accepted as the source's own label CHEMBL1672002 ↗ |
| Known as | P-mentha-3,6-diene-2,5-dione | ChEMBL registry synonym — accepted as the source's own label CHEMBL1672002 ↗ |
| Known as | Thymoquinon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1672002 ↗ |
| Action | Inhibit | “The anti-inflammatory properties of black seeds and thymoquinone are primarily mediated by COX-2 and PGD2 inhibition.” NCT06508372 ↗ |
| Modality | Small molecule | — CHEMBL1672002 ↗ |
| Route | Oral | “Patients in Group B, received a combination of Metformin 500 mg three times daily with meals (Metfor® 500 mg, Metformin hydrochloride tablets. TABUK Pharmaceutical. KSA) and...” NCT04852510 ↗ |