Drugs / NGFR-transduced Autologous T Lymphocytes
last change Apr 2023 re-read 9 days ago

NGFR-transduced Autologous T Lymphocytes

Cell therapy

Developed for
cutaneous melanoma · metastatic melanoma
Investigated by
M.D. Anderson Cancer Center · National Cancer Institute (NCI)

Trials 2

20152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01955460 Oct 2014 → Oct 2027 expected cutaneous melanoma, metastatic melanoma M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01740557 Jan 2015 → Apr 2023 cutaneous melanoma, metastatic melanoma M.D. Anderson Cancer Center Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as NGFR-transduced Autologous T Lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT01740557 ↗
1

NCT01955460 ↗

Action Deplete “Adding these genes to the T cells may help them kill more tumor cells when they are put back in the body.” NCT01955460 ↗
Modality Cell therapy “genetically modified therapeutic autologous lymphocytes (patient's own white blood cells)” NCT01740557 ↗
Route Intravenous “Given IV” NCT01740557 ↗