Drugs / NBM-BMX
last change Apr 2026 re-read 2 minutes ago

NBM-BMX

Small molecule targets HDAC8 via inhibition

Developed for
brain cancer · cancer · uveal melanoma
Investigated by
Novelwise Pharmaceutical Corporation · NatureWise Biotech & Medicals Corporation

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03808870 Dec 2018 → Feb 2022 cancer NatureWise Biotech & Medicals Corporation Completed No outcome recorded
Phase 1 NCT03726294 Oct 2018 → Apr 2020 cancer NatureWise Biotech & Medicals Corporation Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT07569042 Apr 2026 → Sep 2029 expected brain cancer Novelwise Pharmaceutical Corporation Recruiting No outcome recorded
Phase 1/2 NCT07136181 Nov 2025 → Mar 2028 expected uveal melanoma Novelwise Pharmaceutical Corporation Recruiting No outcome recorded
Phase 1/2 NCT06012695 Aug 2023 → May 2028 expected brain cancer Novelwise Pharmaceutical Corporation Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as NBM-BMX ClinicalTrials.gov intervention name — accepted as the source's own label NCT07136181
4

NCT03808870

NCT07569042

NCT03726294

NCT06012695

Action Inhibit “NBM-BMX is a histone deacetylase (HDAC) inhibitor” NCT03726294
Modality Small molecule “NBM-BMX is a new small molecule chemical entity” NCT03726294
Route Oral “Patients will initially receive NBM-BMX orally once a day at 100 mg per day.” NCT03726294
Target HDAC8 “particularly active against HDAC8NCT03726294