Drugs / Personalized neoantigen tumor vaccine
last change Jun 2026 re-read 2 minutes ago

Personalized neoantigen tumor vaccine

also known as XP-004 · XP-006

Messenger RNA (mRNA)

Developed for
B-cell non-Hodgkin lymphoma · cancer · pancreas disorder
Investigated by
Ruijin Hospital · Shanghai Xinpu BioTechnology Company Limited · NeoCura · YueJuan Cheng

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT06496373 Jul 2024 → Jun 2026 overdue pancreas disorder Ruijin Hospital Recruiting No outcome recorded
Phase 11 trial
Phase 1 NCT07334574 Jan 2026 → Jan 2028 expected B-cell non-Hodgkin lymphoma Ruijin Hospital Not yet recruiting No outcome recorded
Phase not applicable1 trial
NCT05359354 Sep 2022 → Sep 2025 cancer YueJuan Cheng Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as personalized neoantigen tumor vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT06496373
1

NCT05359354

Known as XP-004 “This study primarily aims to assess the safety and tolerability of XP-004 personalized mRNA vaccines encoding tumor neoantigens combined with PD-1 inhibitor as adjuvant therapy...” NCT06496373
Known as XP-006 XP-006 personalized tumor mRNA vaccine” NCT07334574
Modality Messenger RNA (mRNA) “mRNA personalized neoantigen tumor vaccine” NCT05359354