Drugs / PCI-27483
last change Aug 2012 re-read 3 minutes ago

PCI-27483

Small molecule targets F7 via inhibition

Developed for
adenocarcinoma · exocrine pancreatic carcinoma
Investigated by
Pharmacyclics LLC.

Trials 1

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01020006 Nov 2009 → Aug 2012 adenocarcinoma, exocrine pancreatic carcinoma Pharmacyclics LLC. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as PCI-27483 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01020006 ↗
Known as Cra-027483 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297315 ↗
Known as PCYC-1001, PCI-27483 Injection “PCYC-1001, PCI-27483 Injection” NCT01020006 ↗
Action Inhibit “Phase II Study of Coagulation Factor VIIa Inhibitor PCI-27483 in Pancreatic Cancer Patients Receiving Treatment With Gemcitabine” NCT01020006 ↗
1

“Coagulation factor VII inhibitor” CHEMBL4297315 ↗

Modality Small molecule — CHEMBL4297315 ↗
Route Subcutaneous “PCI-27483 will be administered as subcutaneous (SC) injections, nominally at a dosage of 1.2 mg/kg BID.” NCT01020006 ↗
Target F7 “Coagulation factor VII inhibitor” CHEMBL4297315 ↗