Drugs / MORF-057
last change Aug 2026 re-read 3 minutes ago

MORF-057

Small molecule

Developed for
ulcerative colitis · Crohn disease
Investigated by
Eli Lilly and Company

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04580745 Sep 2020 → Mar 2021 — Eli Lilly and Company Completed No outcome recorded
Phase 23 trials · 1 met primary · 1 missed
Phase 2 NCT06226883 Jul 2024 → Sep 2028 expected Crohn disease Eli Lilly and Company Recruiting No outcome recorded
Phase 2 NCT05611671 Nov 2022 → Nov 2024 overdue ulcerative colitis Eli Lilly and Company Active not recruiting Missed primary
Phase 2 NCT05291689 Apr 2022 → Oct 2023 ulcerative colitis Eli Lilly and Company Completed Met primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MORF-057 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05611671 ↗
3

NCT05291689 ↗

NCT06226883 ↗

NCT04580745 ↗

Action Inhibit “designed to selectively inhibit integrin α4β7” NCT05291689 ↗
Modality Small molecule “MORF-057 is a small molecule that is designed to selectively inhibit integrin α4β7 and is administered orally.” NCT05291689 ↗
Route Oral “Oral MORF-057” NCT04580745 ↗