Drugs / KER-012
last change Jun 2026 re-read 3 minutes ago

KER-012

Protein / enzyme biologic

Developed for
pulmonary arterial hypertension · diastolic heart failure
Investigated by
Keros Therapeutics, Inc.

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT05975905 Oct 2023 → Mar 2025 pulmonary arterial hypertension Keros Therapeutics, Inc. Terminated No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT07202000 Comparator Jun 2026 → Jul 2027 expected diastolic heart failure Massachusetts General Hospital Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as KER-012 “Activin ligand-trap biological therapy (KER-012) subcutaneously (SC) 1.5mg/kg every 4 weeks X 3” NCT07202000 ↗
1

NCT05975905 ↗

Action Inhibit “activin inhibition” NCT07202000 ↗
Modality Protein / enzyme biologic “activin ligand-trap biological therapy” NCT07202000 ↗
Route Subcutaneous “subcutaneously (SC)” NCT05975905 ↗