Drugs / HER-2 pulsed DC1
last change Feb 2025 re-read 3 minutes ago

HER-2 pulsed DC1

Vaccine

Developed for
breast cancer · HER2 positive breast carcinoma
Investigated by
H. Lee Moffitt Cancer Center and Research Institute · ImmunoRestoration

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT02336984 Jun 2014 → Apr 2016 breast cancer H. Lee Moffitt Cancer Center and Research Institute Withdrawn No outcome recorded
Phase 21 trial
Phase 2 NCT05325632 Oct 2021 → Feb 2027 expected HER2 positive breast carcinoma H. Lee Moffitt Cancer Center and Research Institute Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as HER-2 pulsed DC1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05325632 ↗
1

NCT02336984 ↗

Known as Dendritic Cell (DC1) vaccine “The purpose of the study is to find out if an investigational drug called Dendritic Cell (DC1) vaccine added to standard neoadjuvant (given before main treatment) therapy can...” NCT05325632 ↗
Modality Vaccine “HER-2/Neu Pulsed DC1 Vaccine” NCT02336984 ↗
Route Intrathecal “Treatment included IT delivery of cDC1, 6 times weekly” PMID 39636623 ↗ Feb 2025