Drugs / Narazaciclib
last change Feb 2026 re-read 2 minutes ago

Narazaciclib

also known as HX301 · ON123300

Small molecule

Developed for
cancer · endometrial endometrioid adenocarcinoma · glioma · refractory plasma cell neoplasm
Investigated by
Hangzhou Hanx Biopharmaceuticals, Ltd. · Traws Pharma, Inc. · Adriana Rossi

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04739293 May 2021 → Oct 2024 Traws Pharma, Inc. Unknown No outcome recorded
Phase 1 NCT05731934 Sep 2020 → Jan 2024 cancer Hangzhou Hanx Biopharmaceuticals, Ltd. Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06703255 Jan 2025 → Dec 2026 expected glioma Hangzhou Hanx Biopharmaceuticals, Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06351644 Oct 2024 → Apr 2025 refractory plasma cell neoplasm Adriana Rossi Terminated No outcome recorded
Phase 1/2 NCT05705505 Mar 2023 → Jan 2026 endometrial endometrioid adenocarcinoma Traws Pharma, Inc. Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Narazaciclib ClinicalTrials.gov intervention name — accepted as the source's own label NCT05705505
Known as HX301 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06703255
1

NCT05731934

Known as ON123300 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04739293
1

NCT06351644

Modality Small molecule CHEMBL3115681
Route Oral “Administered Orally as Escalating Daily Doses” NCT04739293