Drugs / Autologous MUC1-activated T-cells
last change Sep 2024 re-read 2 minutes ago

Autologous MUC1-activated T-cells

Cell therapy targets MUC1 via depletion

Developed for
fallopian tube carcinosarcoma · ovarian carcinosarcoma · plasma cell myeloma · primary peritoneal carcinoma
Investigated by
Mayo Clinic

Trials 2 · a red edge is where a trial was stopped

202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06483048 Sep 2024 → Sep 2028 expected fallopian tube carcinosarcoma, ovarian carcinosarcoma, primary peritoneal carcinoma Mayo Clinic Recruiting No outcome recorded
Phase 1 NCT05411497 Jun 2022 → Aug 2027 expected plasma cell myeloma Mayo Clinic Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Autologous MUC1-activated T-cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT05411497
1

NCT06483048

Action Deplete “may help the body's immune system identify and kill cancer cells.” NCT05411497
Modality Cell therapy “MUC1-activated T cells are made from the body's own T cells.” NCT05411497
Route Intravenous “MUC1-activated T-cells IV over 10 minutes to 1 hour on day 0.” NCT05411497
Target MUC1 “The manufactured T-cells are made to target the MUC1 genetic marker” NCT05411497