Drugs / Sodium Lactate

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) LACTATED RINGER'S IN PLASTIC CONTAINER — 1971-03-22 fda.gov ↗

Trials 10

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 24 trials
Phase 2 NCT05004610 Feb 2025 → Dec 2027 expected brain injury, cardiac arrest, ischemic disease Erasme University Hospital Recruiting No outcome recorded
Phase 2 NCT06634069 Nov 2024 → Oct 2027 expected infectious disease with sepsis, intracranial hypertension University Hospital Pilsen Recruiting No outcome recorded
Phase 2 NCT02776488 Sep 2020 → Dec 2025 traumatic brain injury University of California, Los Angeles Withdrawn No outcome recorded
Phase 2 NCT01981655 Dec 2009 → Feb 2013 heart failure Nepean Blue Mountains Local Health District Completed No outcome recorded
Phase 2/33 trials · 1 met primary
Phase 2/3 NCT03528213 Oct 2019 → Feb 2023 infectious disease with sepsis University Hospital, Lille Completed No outcome recorded
Phase 2/3 NCT00995683 Jun 2009 → May 2011 traumatic brain injury Institut d'Anesthesiologie des Alpes Maritimes Completed Met primary
Phase 2/3 NCT00319345 Nov 2003 → Nov 2005 intracranial hypertension, traumatic brain injury Institut d'Anesthesiologie des Alpes Maritimes Terminated No outcome recorded
Phase 31 trial · 1 missed
Phase 3 NCT04488874 Sep 2020 → May 2023 intracranial hypertension Centre Hospitalier Universitaire de Besancon Completed Missed primary
Phase not applicable2 trials
— NCT03286816 Nov 2016 → May 2017 type 1 diabetes mellitus Radboud University Medical Center Completed No outcome recorded
— NCT01455376 Mar → Jun 2010 traumatic brain injury Padjadjaran University Completed No outcome recorded
Comparator or background therapy2 trials
Phase 2 NCT06701760 Comparator Jan 2028 → Dec 2035 expected traumatic brain injury University of California, Los Angeles Not yet recruiting No outcome recorded
— NCT04299815 Comparator Apr → Jul 2020 lactic acidosis University of Aarhus Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as Sodium Lactate ClinicalTrials.gov intervention name — accepted as the source's own label NCT04299815 ↗
11

NCT02776488 ↗

NCT03286816 ↗

NCT04488874 ↗

NCT01455376 ↗

NCT03528213 ↗

NCT00319345 ↗

NCT01981655 ↗

NCT00995683 ↗

NCT05004610 ↗

NCT06701760 ↗

Show 1 more source

Known as HSL “The aim of this study was to assess the clinical effectiveness of intravenous hypertonic sodium lactate (HSL) for intra-operative brain relaxation in supratentorial brain...” PMID 42109031 ↗ May 2026
Modality Other / unclassified “a newly designed crystalloid solution, 0.5 M sodium lactate” NCT01981655 ↗
Route Intravenous “intravenous infusion” NCT01455376 ↗