Drugs / JNJ-38877618
last change May 2020 re-read 3 minutes ago

JNJ-38877618

also known as OMO-1

Small molecule targets MET via inhibition

Developed for
neoplasm
Investigated by
Janssen Cilag N.V./S.A. · Octimet Oncology N.V.

Trials 2

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01964872 Nov 2013 → May 2014 — Janssen Cilag N.V./S.A. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03138083 Aug 2017 → May 2020 neoplasm Octimet Oncology N.V. Terminated No outcome recorded Stop: Business

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as JNJ-38877618 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01964872 ↗
Known as OMO-1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03138083 ↗
Action Inhibit “OMO-1 is a small molecule inhibitor of the enzymatic activity of the MET receptor tyrosine kinase” NCT03138083 ↗
Modality Small molecule “OMO-1 is a small molecule inhibitor of the enzymatic activity of the MET receptor tyrosine kinase” NCT03138083 ↗
1

CHEMBL5095255 ↗

Route Oral “Single ascending dose administered orally in liquid formulation (Formulation A).” NCT01964872 ↗
Target MET “OMO-1 is a small molecule inhibitor of the enzymatic activity of the MET receptor tyrosine kinase” NCT03138083 ↗