Drugs / Casdozokitug
last change Jul 2025 re-read 2 minutes ago

Casdozokitug

also known as CHS-388 · SRF388

Monoclonal antibody

Developed for
hepatocellular carcinoma · clear cell renal carcinoma · non-small cell lung carcinoma
Investigated by
Coherus Oncology, Inc. · Merck Sharp & Dohme LLC

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04374877 Apr 2020 → May 2025 clear cell renal carcinoma, hepatocellular carcinoma, non-small cell lung carcinoma Coherus Oncology, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT06679985 Dec 2024 → Sep 2027 expected hepatocellular carcinoma Coherus Oncology, Inc. Active not recruiting No outcome recorded
Phase 2 NCT05359861 Apr 2022 → Jun 2025 hepatocellular carcinoma Coherus Oncology, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Casdozokitug ClinicalTrials.gov intervention name — accepted as the source's own label NCT06679985
Known as CHS-388 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04374877
Known as SRF388 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05359861
Action Inhibit Inhibition of IL-27 with CHS-388 reduces STAT1 phosphorylation” NCT04374877
Modality Monoclonal antibody CHEMBL5314661
Route Intravenous “SRF388 will be administered by intravenous injection (IV)” NCT05359861