Drugs / ADL5859
last change Jun 2010 re-read 2 minutes ago

ADL5859

Small molecule targets OPRD1 via activation

Developed for
neuropathy, painful · osteoarthritis, knee · peripheral neuropathy · rheumatoid arthritis
Investigated by
Merck & Co., Inc. · Pfizer

Trials 4 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00979953 Oct 2009 → Apr 2010 osteoarthritis, knee Merck & Co., Inc. Completed No outcome recorded
Phase 2 NCT00603265 Nov 2007 → Aug 2008 neuropathy, painful, peripheral neuropathy Merck & Co., Inc. Completed No outcome recorded
Phase 2 NCT00626275 Oct 2007 → Sep 2008 rheumatoid arthritis Merck & Co., Inc. Completed No outcome recorded
Phase 2 NCT00993863 Jun → Sep 2007 Merck & Co., Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ADL5859 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00993863
3

NCT00979953

NCT00603265

NCT00626275

Action Activate “Delta opioid receptor agonist” CHEMBL494480
Modality Small molecule CHEMBL494480
Route Oral “administered orally” NCT00603265
Target OPRD1 “Delta opioid receptor agonist” CHEMBL494480