Drugs / Eloralintide
last change Aug 2026 re-read 2 minutes ago

Eloralintide

also known as LY3841136 · AMY-1176 · Eloralintida

Protein / enzyme biologic

Developed for
obesity disorder · obstructive sleep apnea syndrome · osteoarthritis · type 2 diabetes mellitus
Investigated by
Eli Lilly and Company

Trials 19 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT07701083 Jul → Oct 2026 expected Eli Lilly and Company Not yet recruiting No outcome recorded
Phase 1 NCT07665879 Jun 2026 → Aug 2027 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 1 NCT07426380 Feb → Oct 2026 expected chronic renal failure syndrome, end stage renal failure, impaired renal function disease Eli Lilly and Company Recruiting No outcome recorded
Phase 1 NCT07401862 Feb 2026 → Mar 2027 expected liver disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 1 NCT06916091 Apr → Sep 2025 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06916065 Apr 2025 → Jan 2026 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06297616 Apr 2024 → Nov 2025 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT06345066 Apr 2024 → Sep 2025 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT05295940 Mar 2022 → Jan 2024 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 25 trials
Phase 2 NCT07589608 May 2026 → Sep 2027 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 2 NCT07215559 Oct 2025 → Mar 2027 expected obesity disorder, type 2 diabetes mellitus Eli Lilly and Company Recruiting No outcome recorded
Phase 2 NCT06603571 Sep 2024 → Jul 2026 overdue obesity disorder Eli Lilly and Company Active not recruiting No outcome recorded
Phase 2 NCT06230523 Feb 2024 → May 2025 obesity disorder Eli Lilly and Company Completed No outcome recorded
Phase 2 NCT06143956 Nov 2023 → Sep 2027 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 35 trials
Phase 3 NCT07392190 Feb 2026 → Jun 2028 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 3 NCT07369011 Feb 2026 → Mar 2028 expected obesity disorder, obstructive sleep apnea syndrome Eli Lilly and Company Recruiting No outcome recorded
Phase 3 NCT07353931 Feb 2026 → Mar 2028 expected obesity disorder, osteoarthritis Eli Lilly and Company Recruiting No outcome recorded
Phase 3 NCT07321886 Feb 2026 → Mar 2028 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded
Phase 3 NCT07282600 Dec 2025 → Jan 2028 expected obesity disorder Eli Lilly and Company Recruiting No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 21 sources stand behind the page.

FieldValueCited text
Known as Eloralintide Eloralintide (LY3841136), a novel amylin analog, was evaluated in translational studies to characterize its therapeutic potential for treating obesity.” PMID 41109426 Oct 2025
12

NCT07369011

NCT06916065

NCT06230523

NCT07353931

NCT07215559

NCT07282600

NCT07392190

NCT07589608

NCT07701083

NCT07321886

NCT06916091

NCT07665879

Known as AMY-1176 ChEMBL registry synonym — accepted as the source's own label CHEMBL6068462
Known as Eloralintida ChEMBL registry synonym — accepted as the source's own label CHEMBL6068462
Known as LY3841136 “A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity” NCT06916065
7

NCT05295940

NCT07401862

NCT06345066

NCT06603571

NCT06143956

NCT07426380

NCT06297616

Action Activate “Eloralintide preferentially activated human AMY1R” PMID 41109426 Oct 2025
Modality Peptide “Eloralintide (LY3841136), a novel amylin analog, was evaluated in translational studies to characterize its therapeutic potential for treating obesity.” PMID 41109426 Oct 2025
Modality Protein / enzyme biologic CHEMBL6068462
Route Subcutaneous “Single ascending doses of LY3841136 administered subcutaneously (SC).” NCT05295940