Drugs / Piperine
Trials 8
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT06242535 | Jul 2023 → May 2024 | cognitive disorder, depressive disorder, hyperlipidemia, hypertensive disorder +1 | Hoskinson Health and Wellness Clinic | Completed | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT03201835 | Sep → Dec 2015 | — | PhytoTech Therapeutics, Ltd. | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT05083546 | Dec 2024 → Dec 2025 | obesity disorder | University of California, San Francisco | Withdrawn | No outcome recorded Stop: Business |
| Phase 1/2 | NCT01383694 | Jun 2011 → Feb 2012 | — | Hospital de Mataró | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT04731844 | Dec 2021 → Sep 2024 | monoclonal gammopathy of uncertain significance, prostate cancer, smoldering plasma cell myeloma | University of Rochester | Completed | No outcome recorded |
| Phase 2 | NCT05430087 | Mar 2020 → Jan 2022 | systemic lupus erythematosus | Saiful Anwar Hospital | Completed | No outcome recorded |
| Phase not applicable2 trials · 1 missed | ||||||
| — | NCT05735626 | Jul 2021 → Dec 2023 | disorder of pharynx, stroke disorder | Hospital de Mataró | Unknown | No outcome recorded |
| — | NCT00113841 | Nov 2004 → Aug 2009 | plasma cell myeloma | M.D. Anderson Cancer Center | Completed | Missed primary |
| Comparator or background therapy1 trial | ||||||
| Phase 0 | NCT03845322 Background | Dec 2018 → Feb 2020 | — | University of New Mexico | Withdrawn | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 11 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Piperine | “It was recently detected that combining CC with piperine (black pepper extract, also known as peperine or BioPerine), a known inhibitor of hepatic and intestinal...” NCT03845322 ↗7“Each capsule is a combination of vitamins and natural products: Vitamin B1 (100mg); Vitamin B6 (50mg); Niacin (200mg); Alpha Lipoic Acid (150mg); and Piperine (15mg).” NCT06242535 ↗ “2 soft capsules containing a total of 7.2 mg THC, 6.7 mg CBD and 20 mg piperine (Each capsule contains 3.6 mg THC, 3.3 mg CBD and 10 mg piperine)” NCT03201835 ↗ “MGO cocktail containing a combination of alpha-lipoic acid, nicotinamide, thiamine, pyridoxamine, and piperine” NCT05083546 ↗ |
| Known as | BioPerine | “It was recently detected that combining CC with piperine (black pepper extract, also known as peperine or BioPerine), a known inhibitor of hepatic and intestinal...” NCT03845322 ↗ |
| Known as | black pepper extract | “It was recently detected that combining CC with piperine (black pepper extract, also known as peperine or BioPerine), a known inhibitor of hepatic and intestinal...” NCT03845322 ↗ |
| Known as | FEMA NO. 2909 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43185 ↗ |
| Known as | NSC-21727 | ChEMBL registry synonym — accepted as the source's own label CHEMBL43185 ↗ |
| Known as | peperine | “It was recently detected that combining CC with piperine (black pepper extract, also known as peperine or BioPerine), a known inhibitor of hepatic and intestinal...” NCT03845322 ↗ |
| Action | Activate | “piperine, a dual TRPV1/TRPA1 agonist” PMID 24326980 ↗ Dec 2013 |
| Modality | Other / unclassified | “Each capsule is a combination of vitamins and natural products” NCT06242535 ↗ |
| Route | Oral | “Both of the study agents will be taken by mouth two times a day.” NCT00113841 ↗ |
| Target | TRPV1 | “Piperine acts on the oropharyngeal TRPV1” NCT01383694 ↗ |