Drugs / 89Zr-DFO-AP-101
last change Mar 2026 re-read 3 minutes ago

89Zr-DFO-AP-101

also known as [89Zr]Zr-DFO-AP-101

targets SOD1

Investigated by
Chorus Wellness Inc. · Eli Lilly and Company · University of Sherbrooke

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05974579 Nov 2023 → Dec 2024 amyotrophic lateral sclerosis University of Sherbrooke Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 89Zr-DFO-AP-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05974579 ↗
Known as [89Zr]Zr-DFO-AP-101 “A phase I study to evaluate the dosimetry and safety of [(89)Zr]Zr-DFO-AP-101, a new antibody-based radiopharmaceutical to detect misfolded SOD1 in amyotrophic lateral sclerosis.” PMID 41872337 ↗ Mar 2026
1

“The primary goal of this phase I study is evaluating the safety and biodistribution of the new tracer \[89Zr\]Zr-DFO-AP-101 in healthy volunteers and ALS patients.” NCT05974579 ↗

Route Intravenous “a single intravenous dose” NCT05974579 ↗
Target SOD1 “targeting mSOD1” PMID 41872337 ↗ Mar 2026