Drugs / hydroxypropylmethylcellulose
last change Feb 2026 re-read 8 days ago

hydroxypropylmethylcellulose

Developed for
dry eye syndrome · corneal edema · eye adnexa disorder
Investigated by
Mahidol University · Niğde State Hospital · Superior University · University of Sao Paulo

Trials 4

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 42 trials
Phase 4 NCT02752763 Oct 2015 → Mar 2016 dry eye syndrome Niğde State Hospital Completed No outcome recorded
Phase 4 NCT01387620 Jun 2009 → Feb 2010 corneal edema University of Sao Paulo Completed No outcome recorded
Phase not applicable2 trials
— NCT06913387 Mar → Jul 2025 overdue dry eye syndrome Superior University Active not recruiting No outcome recorded
— NCT01284439 Jan 2011 → Jan 2012 eye adnexa disorder, glaucoma Mahidol University Unknown No outcome recorded
Comparator or background therapy4 trials
Phase 2 NCT03693183 Comparator Mar → Jun 2009 dry eye syndrome ORA, Inc. Withdrawn No outcome recorded
Phase 2 NCT00583466 Comparator May 2007 → May 2008 gastrointestinal polyp Johns Hopkins University Completed No outcome recorded
Phase 4 NCT06859476 Comparator May → Sep 2025 — Laboratorios Sophia S.A de C.V. Completed No outcome recorded
Phase 4 NCT01280110 Comparator Mar → Dec 2011 dry eye syndrome University of Campinas, Brazil Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as hydroxypropyl methylcellulose “preservative free artificial tears drop(hydroxypropyl methylcellulose or carboxymethyl cellulose) four times one drop daily.” NCT02752763 ↗
7

“Hydroxypropyl methylcellulose 0.5%. One drop QID, with a minimun interval of 3 hours between administrations, for 7 days.” NCT06859476 ↗

“The intervention involved the administration of SOFTEAL EYE DROPS, which contain Hydroxypropylmethyl Cellulose 0.3%.” NCT06913387 ↗

“Hydroxypropyl methylcellulose (HPMC) will be injected under the lesion to create submucosal cushion” NCT00583466 ↗

“0.80% Hydroxypropyl Methylcellulose solution 4 times per day for 2 days” NCT03693183 ↗

NCT01284439 ↗

NCT01280110 ↗

NCT01387620 ↗

Known as HPMC “Hydroxypropyl methylcellulose (HPMC) will be injected under the lesion to create submucosal cushion” NCT00583466 ↗
Known as Tears naturale free(hydroxypropyl methylcellulose) “Tears naturale free(hydroxypropyl methylcellulose)” NCT02752763 ↗
Route Topical “22 patients will receive this lubricating drop 4 times a day for 1 month” NCT01280110 ↗