Drugs / hydroxypropylmethylcellulose
last change Feb 2026 re-read 2 minutes ago

hydroxypropylmethylcellulose

Developed for
dry eye syndrome · corneal edema · eye adnexa disorder
Investigated by
Mahidol University · Niğde State Hospital · Superior University · University of Sao Paulo

Trials 4 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 42 trials
Phase 4 NCT02752763 Oct 2015 → Mar 2016 dry eye syndrome Niğde State Hospital Completed No outcome recorded
Phase 4 NCT01387620 Jun 2009 → Feb 2010 corneal edema University of Sao Paulo Completed No outcome recorded
Phase not applicable2 trials
NCT06913387 Mar → Jul 2025 overdue dry eye syndrome Superior University Active not recruiting No outcome recorded
NCT01284439 Jan 2011 → Jan 2012 eye adnexa disorder, glaucoma Mahidol University Unknown No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT03693183 Comparator Mar → Jun 2009 dry eye syndrome ORA, Inc. Withdrawn No outcome recorded
Phase 2 NCT00583466 Comparator May 2007 → May 2008 gastrointestinal polyp Johns Hopkins University Completed No outcome recorded
Phase 42 trials
Phase 4 NCT06859476 Comparator May → Sep 2025 Laboratorios Sophia S.A de C.V. Completed No outcome recorded
Phase 4 NCT01280110 Comparator Mar → Dec 2011 dry eye syndrome University of Campinas, Brazil Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Hydroxypropyl methylcellulose “preservative free artificial tears drop(hydroxypropyl methylcellulose or carboxymethyl cellulose) four times one drop daily.” NCT02752763
7

Hydroxypropyl methylcellulose 0.5%. One drop QID, with a minimun interval of 3 hours between administrations, for 7 days.” NCT06859476

“The intervention involved the administration of SOFTEAL EYE DROPS, which contain Hydroxypropylmethyl Cellulose 0.3%.” NCT06913387

Hydroxypropyl methylcellulose (HPMC) will be injected under the lesion to create submucosal cushion” NCT00583466

“0.80% Hydroxypropyl Methylcellulose solution 4 times per day for 2 days” NCT03693183

NCT01387620

NCT01284439

NCT01280110

Known as HPMC “Hydroxypropyl methylcellulose (HPMC) will be injected under the lesion to create submucosal cushion” NCT00583466
Known as Tears naturale free(hydroxypropyl methylcellulose) Tears naturale free(hydroxypropyl methylcellulose)NCT02752763
Route Topical “22 patients will receive this lubricating drop 4 times a day for 1 month” NCT01280110